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1 Apr, 2021 00:55

Xenobots 2.0? Scientists create improved biological robots from frog cells capable of ‘swarm’ behavior, memory & self-healing

Researchers have developed new and improved xenobots, tiny biological machines constructed from frog cells that are now able to organize themselves into a single body as a ‘swarm’ and even ‘remember’ their surroundings.

The upgraded bots built on work first unveiled by scientists at Tufts University and the University of Vermont last year, improving on the design to allow them to move faster, live longer and assemble themselves to work collectively as one unit, a process known as “cellular self-organization.” Outlined in an article for the Science Robotics journal on Wednesday, the breakthrough could shed light on “swarm intelligence” in the animal kingdom and beyond.

“Roboticists have been looking at swarm intelligence for a long time, biologists have been studying swarm intelligence in organisms. This is something in between, which I think is kind of interesting,” said University of Vermont researcher Josh Bongard.

It sort of suggests, to me at least as a roboticist, is this a better path to making swarms of useful machines than it is to make swarms out of traditional robotic parts?


The researchers also said their work showed that a “writable molecular memory” is possible, giving the xenobots the ability to “record exposure to a specific wavelength of light” using a special type of protein that turns red when exposed to blue light.

While the earlier iteration relied on the contraction of muscle cells for movement, the new model uses hair-like structures on its surface known as cilia, allowing it to crawl and swim around faster. Still capable of self-healing, the updated version is also able to survive for three to seven days longer than its forerunner, which only lasted for about a week.


“Together, these results introduce a platform that can be used to study many aspects of self-assembly, swarm behavior, and synthetic bioengineering, as well as provide versatile, soft-body living machines for numerous practical applications in biomedicine and the environment,” the scientists said.

Also on rt.com Xenobots are here: Tiny bio-robots inside your veins may heal you & will definitely be weaponized by West to take out ‘bad guys’

Standing at between one-quarter and one-half a millimeter in size, the organic machines were designed with the help of a supercomputer, which used an evolutionary algorithm to generate microscopic blueprints. They are made from stem cells harvested from frog embryos and are completely biodegradable, raising hopes they could someday be safely used in the human body and for environmental clean-up. The researchers did not address the prospect that the bots could be weaponized or used for military applications, though the Pentagon’s advanced research wing, DARPA, has toyed with similar ideas in the past. 

Straddling the boundary between biology and inanimate tech, classifying the zombie-like robots has proven more difficult, as the researchers suggest they may have created a wholly new class of lifeform.

“I don’t feel any closer to an answer. Whether these are robots, whether these are frogs, whether these are something else entirely,” said Bongard.

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