icon bookmark-bicon bookmarkicon cameraicon checkicon chevron downicon chevron lefticon chevron righticon chevron upicon closeicon v-compressicon downloadicon editicon v-expandicon fbicon fileicon filtericon flag ruicon full chevron downicon full chevron lefticon full chevron righticon full chevron upicon gpicon insicon mailicon moveicon-musicicon mutedicon nomutedicon okicon v-pauseicon v-playicon searchicon shareicon sign inicon sign upicon stepbackicon stepforicon swipe downicon tagicon tagsicon tgicon trashicon twicon vkicon yticon wticon fm

Brain damage on the rise among well-off, middle-age drinkers

Brain damage on the rise among well-off, middle-age drinkers
Brain damage among drinkers aged 50 and above has trebled in the last ten years, with experts fearing the issue is under-reported in the middle classes.

Newly released figure show that 3,627 drinkers over the age of 50 were admitted to hospital with alcohol-related brain damage in 2015 compared with 994 in 2002.

Related symptoms include memory loss, loss of balance, and recalling events that didn’t happen. It is feared that many middle-class drinkers are suffering some degree of brain damage and not understanding how seriously their daily wine intake can affect them.

In services around the country, people are seeing [a level of] drinkers they would not have seen five or ten years ago,” consultant psychiatrist Tony Rao told the Times on Thursday.

He said social class may be a key issue because, “if an educated woman turns up at a GP surgery or A&E with a fall, no one asks about her alcohol intake.

A genome study of 105,000 people carried out by researchers from King’s College London and Imperial College London appeared to show that having a taste for drink might be genetic.

They found the hormone FGF21, which is secreted by the liver, plays a crucial role in setting a person’s drinking limits.

The study highlighted the “pathway” between the hormone and a gene in the brain called beta-Klotho. In about 40 percent of participants, a particular beta-Klotho variant was associated with reduced alcohol consumption.

Further investigation found that those lacking the beta-Klotho gene show a significant increase in alcohol consumption.

Scientists say the discovery will lead to new treatments for people unable to control their drinking, as it may be possible to replicate the gene’s function, researchers say.

Professor Gunter Schumann, from the Institute of Psychiatry at King’s College London, told the Sun: “Our study reveals a previously unrecognized liver-brain pathway which regulates alcohol consumption in humans, and which could one day be targeted therapeutically to suppress consumption in problem drinkers.