An aging African-American Muslim confronts his memories of medical experiments conducted on him as an inmate in Philadelphia. An Army medic struggles with failed PTSD treatments. A woman mourns her son who committed suicide while taking part in an antidepressant marketing study. These are the medicated margins, those who've gone ‘off-label’ – a term that refers to the use of pharmaceuticals in ways counter to their prescribed dosage or function. These are men and women for whom pharmaceutical use, abuse and misuse are simply a way of life in a society that pathologizes the individual's desire for health and happiness – and even identity – for profit.
Weaving together the moving and personal stories of these people and many more, Michael Palmieri and Donal Mosher expose the breadth of off-label drug use and take us on an emotional road trip through an overmedicated, misdiagnosed and drug-addled America.