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Printing new organs – sci-fi becomes true

Published: 15 February, 2010, 07:17
Edited: 19 February, 2010, 10:47

(13.4Mb) embed video

TAGS: Health, Russia, SciTech


Patients in need of a transplant know they could face a dangerously long wait. But now scientists may have some good news on the horizon - as human organs in the future may simply be printed out.

Bio-printing technology is being developed by a leading Moscow research centre, a breakthrough that for some could be a matter of life and death.

Tatyana Romantsova is one of the transplant patients. She is in year three of her new life. She is grateful for it and for the time she gets to spend with her daughter. In 2007 Tatyana was suffering from a sickness that threatened to take her away from her family.

Tatyana’s heart could not pump properly as she was diagnosed with dilated cardiomyopathy. Only a heart transplant could save her.

“They put me on the waiting list, my health was failing and I was waiting,” Tatyana recalls. “But I had strong faith that it was not in vain. I had something to live for – a child, a family. I waited for 8 months.”

Thousands around the world die every year waiting on transplant lists.

“Of course, the lack of donor organs is a big problem,” Romantsova claims. “There are so many people who never get this chance to walk and be happy again. So many lose their close ones. We, patients at the institute, also see just the tip of the iceberg because very few actually get to this hospital.”

But what if scientists could save more lives by growing organs on demand?


Click to enlarge
Dr. Vladimir Vasilets is head researcher at the Federal Scientific Research Centre of Transplantology and Bioartificial organs in Moscow. He and his team are working on copying cells to eventually print organs.

“The possibility of creating such bio-artificial fragments of tissues and, in some distant future, of organs, will solve many problems transplantology is now facing,” Vasilets says. “Such possibilities will be the ultimate for a person who has tried all other remedies.”

They are now using a bio-printer. A cartridge of bio-ink containing materials such as proteins and peptides is snapped into a printer followed by cell-friendly biopaper.

Scientist then use a computer to tell the printer the desired shape the matter should take. After processing the commands, the machine performs like a laser jet printer dropping individual ink clusters onto the paper. The clusters fuse together and as the layers of matter build, the structure becomes more complex and eventually the biopaper dissolves.

The ultimate goal is to take patients' cells and use a printer to grow an organ their bodies will be less likely to refuse. Now, that technology is many years off, but what scientists foresee happening in the short term is being able to grow large amounts of tissues they could used for drug trials, bypassing the use of animals and humans.

Tatyana Romantsova hopes scientists will quickly learn how to take this process from the experimental to daily use.

“It would be great, may God help the scientists in this,” she says. “People will be able to live, and live fuller lives, not taking immuno-suppressants that have multiple side effects. It is going to be your own heart, which your system will be friendly to.”

Professor Simon Matskeplishvili, a cardiologist, told RT: “People would know that this isn’t a cheap thing, this would be a very expensive procedure, very difficult procedure – and not for everybody until 10-15 years [from now].”

Watch interview with Simon Matskeplishvili

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Bru Raczin February 19, 2010, 04:05
0

It seems too good to be true, and anything that sounds too good to be true probably is. For now, science has claimed to have "mapped the human genome." All well and good, but Who can actually read the map? No one knows what all those codons actually "print out" and even if one could re-create an organ, the human histocompatabiltiy complex is so overwhelmingly intricate to just crank out "clones" of a persons organs and not have them rejected. Not impossible, but not so fast!

Epsilon February 16, 2010, 22:17
0

This isnt a completely new idea, the method has been researched internationally for years now (altough the russian method may have some twists). Scientists have also made organs in other ways. Perhaps the most impressive are the blatters that have been grown from the original blatter cells of young childs (with deffect blatters), put into their systems and still work perfectly, 10 years after. But of course, this method opens up for the construction of far more complicated organs and, unlike Katrina who seems to thank God for this, I truly respect those who are making this dream a reality. Great to see that Russian scientist is taking part of this scientific adventure. The potential is huge.

Katrina February 15, 2010, 18:35
0

This is brilliant scientific discovery and a giant leap forward for medical research. God bless Russian scientists.